SigI

• Description: RNA polymerase sigma factor SigI
  
  

Gene name	sigI
Synonyms	ykoZ
Essential	no
Product	RNA polymerase sigma factor SigI
Function	control of a class of heat shock genes
Metabolic function and regulation of this protein in SubtiPathways: Stress
MW, pI	29 kDa, 8.306
Gene length, protein length	753 bp, 251 aa
Immediate neighbours	ykoY, rsgI
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

transcription, sigma factors and their control, heat shock proteins

This gene is a member of the following regulons

SigI regulon

The gene

Basic information

• Locus tag: BSU13450

Phenotypes of a mutant

temperature-sensitive growth on agar plates PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Members of the SigI regulon

gsiB PubMed, mreBH, bcrC PubMed

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • RsgI-SigI, the interaction inhibits SigI activity PubMed
  • SigI-RpoB-RpoC

• Localization:

Database entries

• Structure:

• UniProt: O31654

• KEGG entry: [3]

• E.C. number:

Additional information

overexpression of SigI suppresses mreB mreBH mbl mutants PubMed

Expression and regulation

• Operon: sigI-rsgI PubMed

• Sigma factor: SigI PubMed

• Regulation: induced by heat PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: