YkkE
- Description: formyltetrahydrofolate deformylase
| Gene name | ykkE |
| Synonyms | purU |
| Essential | no |
| Product | formyltetrahydrofolate deformylase |
| Function | purine nucleotide synthesis |
| MW, pI | 34 kDa, 5.949 |
| Gene length, protein length | 900 bp, 300 aa |
| Immediate neighbours | ykkD, proB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU13110
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 10-formyltetrahydrofolate + H2O = formate + tetrahydrofolate (according to Swiss-Prot)
- Protein family: ACT domain (according to Swiss-Prot)
- Paralogous protein(s): PurN
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O34990
- KEGG entry: [2]
- E.C. number: 3.5.1.10
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
