IolT

• Description: major transporter for inositol
  
  

Gene name	iolT
Synonyms	ydjK
Essential	no
Product	major transporter for inositol
Function	myo-inositol uptake
MW, pI	51 kDa, 9.569
Gene length, protein length	1419 bp, 473 aa
Immediate neighbours	ydjJ, bdhA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

transporters/ other, utilization of specific carbon sources, membrane proteins

This gene is a member of the following regulons

IolR regulon

The gene

Basic information

• Locus tag: BSU06230

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: transport of myo-inositol PubMed

• Protein family: View classification (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O34718

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:
  • induced in the presence of inositol (IolR) PubMed

• Regulatory mechanism:
  • IolR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Tetsuro Morinaga, Takatsugu Matsuse, Hitoshi Ashida, Ken-ichi Yoshida
Differential substrate specificity of two inositol transporters of Bacillus subtilis.
Biosci Biotechnol Biochem: 2010, 74(6);1312-4
[PubMed:20530884] [WorldCat.org] [DOI] (I p)

Ken-Ichi Yoshida, Yoshiyuki Yamamoto, Kaoru Omae, Mami Yamamoto, Yasutaro Fujita
Identification of two myo-inositol transporter genes of Bacillus subtilis.
J Bacteriol: 2002, 184(4);983-91
[PubMed:11807058] [WorldCat.org] [DOI] (P p)