YybK

• Description: similar to ABC transporter (membrane protein)
  
  

Gene name	yybK
Synonyms
Essential	no
Product	ABC transporter (membrane protein)
Function	unknown
MW, pI	28 kDa, 9.751
Gene length, protein length	753 bp, 251 aa
Immediate neighbours	yybL, yybJ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU40610

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

ABC transporters, membrane proteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: YybJ-(YybK-YybL) PubMed

• Localization: cell membrane PubMed

Database entries

• Structure:

• UniProt: P37493

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yybN-yybM-yybL-yybK-yybJ (according to [DBTBS])

• Sigma factor:

• Regulation:
  • repressed by Rok PubMed

• Regulatory mechanism:
  • Rok: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Mark Albano, Wiep Klaas Smits, Linh T Y Ho, Barbara Kraigher, Ines Mandic-Mulec, Oscar P Kuipers, David Dubnau
The Rok protein of Bacillus subtilis represses genes for cell surface and extracellular functions.
J Bacteriol: 2005, 187(6);2010-9
[PubMed:15743949] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)