YkoH

• Description: two-component sensor kinase
  
  

Gene name	ykoH
Synonyms
Essential	no
Product	two-component sensor kinase
Function	unknown
MW, pI	50 kDa, 6.167
Gene length, protein length	1362 bp, 454 aa
Immediate neighbours	ykoG, ykoI
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU13260

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Categories containing this gene/protein

protein modification, transcription factors and their control, membrane proteins, phosphoproteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of YkoG

• Protein family:

• Paralogous protein(s): CssS, KinE, YclK, YvrG

Extended information on the protein

• Kinetic information:

• Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain

• Modification: autophosphorylation on a His residue

• Cofactor(s):

• Effectors of protein activity:

• Interactions: YkoH-YkoG

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O34638

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)