TmrB

• Description: tunicamycin resistance protein, ATP-binding membrane protein
  
  

Gene name	tmrB
Synonyms
Essential	no
Product	tunicamycin resistance protein
Function	resistance to tunicamycin
MW, pI	22 kDa, 9.714
Gene length, protein length	591 bp, 197 aa
Immediate neighbours	nadE, aroK
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU03140

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

resistance against toxins/ antibiotics, membrane proteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P12921

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: tmrB (according to DBTBS)

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Y Noda, K Yoda, A Takatsuki, M Yamasaki
TmrB protein, responsible for tunicamycin resistance of Bacillus subtilis, is a novel ATP-binding membrane protein.
J Bacteriol: 1992, 174(13);4302-7
[PubMed:1624425] [WorldCat.org] [DOI] (P p)