GamP

• Description: glucosamine-specific phosphotransferase system, EIICBA of the PTS
  
  

Gene name	gamP
Synonyms	ybfS, yzfA
Essential	no
Product	glucosamine-specific phosphotransferase system, EIICBA
Function	glucosamine uptake and phosphorylation
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	67 kDa, 5.472
Gene length, protein length	1893 bp, 631 aa
Immediate neighbours	gltP, gamA
Gene sequence (+200bp)	Protein sequence
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU02350

Phenotypes of a mutant

delayed growth with glucosamine as the single carbon source PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Categories containing this gene/protein

cell wall degradation/ turnover, phosphotransferase systems, utilization of specific carbon sources, membrane proteins, phosphoproteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: protein EIIA N(pi)-phospho-L-histidine + protein EIIB = protein EIIA + protein EIIB N(pi)-phospho-L-histidine/cysteine (according to Swiss-Prot)

• Protein family: PTS permease, glucose permease (Glc) family PubMed

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot), membrane associated PubMed

Database entries

• Structure:

• UniProt: P39816

• KEGG entry: [2]

• E.C. number: 2.7.1.69

Expression and regulation

• Operon: gamA-gamP

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant: QB6098 (aphA3), available in Stülke lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: