CotM

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  • Description: spore coat protein (outer)

Gene name cotM
Synonyms yneL
Essential no
Product spore coat protein (outer)
Function resistance of the spore
MW, pI 15 kDa, 3.942
Gene length, protein length 390 bp, 130 aa
Immediate neighbours yneK, sspP
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
CotM context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU17970

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

Categories containing this gene/protein

sporulation proteins

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

S Reischl, S Thake, G Homuth, W Schumann
Transcriptional analysis of three Bacillus subtilis genes coding for proteins with the alpha-crystallin domain characteristic of small heat shock proteins.
FEMS Microbiol Lett: 2001, 194(1);99-103
[PubMed:11150673] [WorldCat.org] [DOI] (P p)

A O Henriques, B W Beall, C P Moran
CotM of Bacillus subtilis, a member of the alpha-crystallin family of stress proteins, is induced during development and participates in spore outer coat formation.
J Bacteriol: 1997, 179(6);1887-97
[PubMed:9068633] [WorldCat.org] [DOI] (P p)