CotE

• Description: spore coat protein (outer)
  
  

Gene name	cotE
Synonyms
Essential	no
Product	spore coat protein (outer)
Function	assembly of CotC-CotU complex
MW, pI	20 kDa, 4.139
Gene length, protein length	543 bp, 181 aa
Immediate neighbours	ymcA, mutS
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU17030

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

sporulation proteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: assembly of the CotC-CotU complex PubMed

• Protein family: cotE family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: homotypic interaction PubMed, CotE-CotC PubMed, CotE-CotU PubMed

• Localization: spore wall (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P14016

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: cotE PubMed

• Sigma factor: SigE PubMed, SigK PubMed

• Regulation:
  • repressed by casamino acids PubMed
  • expressed during sporulation in the mother cell (SigE, SigK) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Arthur Aronson, Purdue University, West Lafayette, USA homepage

Adriano Henriques, Lisbon, Portugal homepage