SpeE

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• Description: spermidine synthase <br/><br/>

Gene name	speE
Synonyms	ywhF
Essential	no
Product	spermidine synthase
Function	spermidine, polyamine biosynthesis
Metabolic function and regulation of this protein in SubtiPathways: <br/>Cys, Met & Sulfate assimilation
MW, pI	31 kDa, 5.068
Gene length, protein length	828 bp, 276 aa
Immediate neighbours	speB, pbpG
Get the DNA and protein sequences <br/> (Barbe et al., 2009)
Genetic context <br/> <div align="right"> <small>This image was kindly provided by SubtiList</small></div>

<br/><br/><br/><br/><br/><br/>

The gene

Basic information

• Locus tag: BSU37500

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: S-adenosylmethioninamine + putrescine = 5'-S-methyl-5'-thioadenosine + spermidine (according to Swiss-Prot)

• Protein family: spermidine/spermine synthase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 1IY9

• UniProt: P70998

• KEGG entry: [3]

• E.C. number: 2.5.1.16

Expression and regulation

• Operon:
  • speE-speB PubMed
  • speE PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

<pubmed> 9723923</pubmed>