cypC
168
long chain-fatty acid beta-hydroxylating cytochrome P450, H(2)O(2)-dependent, hydroxylates myristic acid to beta-hydroxymyristic acid, required for protection against paraquat stress
Locus
BSU_02100
Molecular weight
47.95 kDa
Isoelectric point
6.47
Function
biosynthesis of beta-hydroxy fatty acid for lipopeptides
Product
fatty acid beta-hydroxylating cytochrome P450, protection against paraquat stress
Essential
no
E.C.
null
Synonyms
cypC, ybdT
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2124 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
229,525 230,778
The protein
Catalyzed reaction/ biological activity
hydroxylation of a long-chain fatty acid (e.g. myristic acid) at the alpha- and beta-positions using hydrogen peroxide as an oxidant PubMed
1,2-saturated fatty acid + H2O2 --> 2-hydroxy fatty acid + H2O (according to UniProt)
2,3-saturated fatty acid + H2O2 --> 3-hydroxy fatty acid + H2O (according to UniProt)
Protein family
cytochrome P450 family (according to UniProt)
Structure
Expression and Regulation
Operons
Biological materials
Mutant
MGNA-B961 (ybdT::erm), available at the NBRP B. subtilis, Japan
References
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Time of last update: 2025-01-03 14:50:12
Author of last update: Melvin.boenninger