AraP

• Description: L-arabinose ABC transporter (integral membrane protein)
  
  

Gene name	araP
Synonyms	yseD
Essential	no
Product	L-arabinose ABC transporter (integral membrane protein))
Function	uptake of arabinose
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	34 kDa, 9.69
Gene length, protein length	939 bp, 313 aa
Immediate neighbours	araQ, araN
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU28740

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: MalFG subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: AraN(2)-(AraP-AraQ)-MsmX PubMed

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P94529

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: araA-araB-araD-araL-araM-araN-araP-araQ-abfA PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed by glucose (CcpA) PubMed
  • induced by arabinose (AraR) PubMed

• Regulatory mechanism:
  • CcpA: transcription repression PubMed
  • AraR: transcription repression PubMed

• Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: