SpoVS

• Description: required for dehydratation of the spore core and assembly of the coat, mutation increases SigD-dependent gene expression, might act via SinR
  
  

Gene name	spoVS
Synonyms
Essential	no
Product	unknown
Function	spore coat assembly, spore core dehydratation
MW, pI	8 kDa, 6.475
Gene length, protein length	258 bp, 86 aa
Immediate neighbours	ymdB, tdh
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU16980

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P45693

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: spoVS PubMed

• Sigma factor: SigH PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:
  • The mRNA has a long 5' leader region. This may indicate RNA-based regulation PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Irnov Irnov, Cynthia M Sharma, Jörg Vogel, Wade C Winkler
Identification of regulatory RNAs in Bacillus subtilis.
Nucleic Acids Res: 2010, 38(19);6637-51
[PubMed:20525796] [WorldCat.org] [DOI] (I p)

Daniel J Rigden, Michael Y Galperin
Sequence analysis of GerM and SpoVS, uncharacterized bacterial 'sporulation' proteins with widespread phylogenetic distribution.
Bioinformatics: 2008, 24(16);1793-7
[PubMed:18562273] [WorldCat.org] [DOI] (I p)

O Resnekov, A Driks, R Losick
Identification and characterization of sporulation gene spoVS from Bacillus subtilis.
J Bacteriol: 1995, 177(19);5628-35
[PubMed:7559352] [WorldCat.org] [DOI] (P p)