RnmV

• Description: RNase M5
  
  

Gene name	rnmV
Synonyms	yabF
Essential	no
Product	endoribonuclease M5
Function	5S ribosomal RNA maturation
MW, pI	20 kDa, 6.681
Gene length, protein length	558 bp, 186 aa
Immediate neighbours	yabE, ksgA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU00410

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: N-terminal part: Toprim domain PubMed

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (homogeneous) PubMed

Database entries

• Structure:

• UniProt: P37547

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: rnmV-ksgA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Ciaran Condon, IBPC, Paris, France Homepage

References

Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537] [WorldCat.org] [DOI] (P p)

Frédéric Allemand, Nathalie Mathy, Dominique Brechemier-Baey, Ciarán Condon
The 5S rRNA maturase, ribonuclease M5, is a Toprim domain family member.
Nucleic Acids Res: 2005, 33(13);4368-76
[PubMed:16077031] [WorldCat.org] [DOI] (I e)

Ciarán Condon, Jordi Rourera, Dominique Brechemier-Baey, Harald Putzer
Ribonuclease M5 has few, if any, mRNA substrates in Bacillus subtilis.
J Bacteriol: 2002, 184(10);2845-9
[PubMed:11976317] [WorldCat.org] [DOI] (P p)

C Condon, D Brechemier-Baey, B Beltchev, M Grunberg-Manago, H Putzer
Identification of the gene encoding the 5S ribosomal RNA maturase in Bacillus subtilis: mature 5S rRNA is dispensable for ribosome function.
RNA: 2001, 7(2);242-53
[PubMed:11233981] [WorldCat.org] [DOI] (P p)