Sandbox

• Description: regulatory RNA
  
  

Gene name	fsrA
Synonyms	mrgC
Essential	no
Product	sRNA FsrA
Function	inhibition of sdhC translation
Gene length	aaa bp
Immediate neighbours	ykuI, ykuJ
Gene sequence (+200bp)
Genetic context

The gene

Basic information

• Locus tag:

Database entries

• DBTBS entry: no entry

• SubtiList entry: no entry

• Structure:

Additional information

• Swiss prot entry:

• KEGG entry: no entry

• E.C. number:

The RNA

Basic information/ Evolution

• Catalyzed reaction/ biological activity: hybridizes to sdhC, citB, lutB, and leuC-leuD mRNAs and inhibits their translation. PubMed

Extended information on the RNA

• Kinetic information

• Interactions: Binds sdhC, citB, lutB, and leuC-leuD mRNAs PubMed

• Localization

Database entries

• Structure:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation: induced by iron starvation (Fur) PubMed

• Regulatory mechanism: Fur: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

Labs working on this gene/RNA

John Helmann, Cornell University, USA Homepage

References

Ahmed Gaballa, Haike Antelmann, Claudio Aguilar, Sukhjit K Khakh, Kyung-Bok Song, Gregory T Smaldone, John D Helmann
The Bacillus subtilis iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteins.
Proc Natl Acad Sci U S A: 2008, 105(33);11927-32
[PubMed:18697947] [WorldCat.org] [DOI] (I p)

1. Gaballa A, Antelmann H, Aguilar C, Khakh SK, Song KB, Smaldone GT, Helmann JD (2008) The Bacillus subtilis iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteins. PNAS 105: 11927-11932. PubMed
2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed