Sandbox
- Description: spore coat protein (insoluble fraction)
| Gene name | cotX |
| Synonyms | |
| Essential | no |
| Product | spore coat protein (insoluble fraction) |
| Function | resistance of the spore |
| MW, pI | 18 kDa, 4.228 |
| Gene length, protein length | 516 bp, 172 aa |
| Immediate neighbours | cotY, cotW |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU11760
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: spore wall (according to Swiss-Prot)
Database entries
- Structure:
- Swiss prot entry: Q08313
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
cotX PubMed
- Sigma factor: before cotV: SigK PubMed
- Regulation: repressed by casamino acids PubMed
- Regulatory mechanism: upstream of cotX: SpoIIID: repression PubMed, upstream of both promoters: GerE: transcription activation PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147]
[WorldCat.org]
[DOI]
(P p)
