LevF

From SubtiWiki
Revision as of 00:50, 3 April 2009 by Sroppel (talk | contribs)
Jump to: navigation, search
  • Description: fructose-specific phosphotransferase system, EIIC component

Gene name levF
Synonyms sacL
Essential no
Product fructose-specific phosphotransferase system,
EIIC component
Function fructose uptake and phosphorylation
MW, pI 27 kDa, 4.395
Gene length, protein length 807 bp, 269 aa
Immediate neighbours levG, levE
Gene sequence (+200bp) Protein sequence
Genetic context
LevF context.gif
This image was kindly provided by SubtiList




The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: repressed by glucose (CcpA) , carbon catabolite repression, induction by fructose
  • Regulatory mechanism: CcpA: transcription repression, catabolite repression: transcription repression by CcpA, transcription activator LevR is less active in the presence of glucose; induction: transcription activation by LevR
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Martin-Verstraete, I., Débarbouillé, M., Klier, A., and Rapoport, G. (1990) Levanase operon of Bacillus subtilis includes a fructose-specific phosphotransferase system regulating the expression of the operon. J Mol Biol 214: 657-671. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed