Ldt

• Description: L,D-transpeptidase involved in cell wall synthesis
  
  

Gene name	ldt
Synonyms	ykuD
Essential	no
Product	L,D-transpeptidase
Function	cell wall biosynthesis
Gene expression levels in SubtiExpress: ldt
MW, pI	17 kDa, 10.252
Gene length, protein length	492 bp, 164 aa
Immediate neighbours	ykuC, ykuE
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components, sporulation proteins

This gene is a member of the following regulons

CcpA regulon, SigK regulon

The gene

Basic information

• Locus tag: BSU14040

Expression

Database entries

• BsubCyc: BSU14040

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:
  • contains a N-acetylglucosamine-polymer-binding LysM domain PubMed

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization:
  • spore wall (according to Swiss-Prot)

Database entries

• BsubCyc: BSU14040

• Structure: 1Y7M

• UniProt: O34816

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:
  • ykuE-ldt-ykuC PubMed
  • ldt PubMed

• Expression browser: ldt PubMed

• Sigma factor: SigK PubMed

• Regulation:
  • repressed by glucose (3.3-fold) (CcpA) PubMed
  • expressed during sporulation in the mother cell (SigK) PubMed

• Regulatory mechanism: CcpA: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Girbe Buist, Anton Steen, Jan Kok, Oscar P Kuipers
LysM, a widely distributed protein motif for binding to (peptido)glycans.
Mol Microbiol: 2008, 68(4);838-47
[PubMed:18430080] [WorldCat.org] [DOI] (I p)