ProG

• Description: 1-pyrroline-5-carboxylate dehydrogenase, the precise role of ProG is unknown
  
  

Gene name	proG
Synonyms	ykeA, yzcA
Essential	no
Product	1-pyrroline-5-carboxylate dehydrogenase
Function	biosynthesis of proline
Gene expression levels in SubtiExpress: proG
Metabolic function and regulation of this protein in SubtiPathways: proG
MW, pI	30 kDa, 4.914
Gene length, protein length	816 bp, 272 aa
Immediate neighbours	htrA, dppA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis/ acquisition of amino acids

The gene

Basic information

• Locus tag: BSU12910

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: L-proline + NAD(P)⁺ = 1-pyrroline-5-carboxylate + NAD(P)H (according to Swiss-Prot)

• Protein family: pyrroline-5-carboxylate reductase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: Q00777

• KEGG entry: [3]

• E.C. number: 1.5.1.2

Expression and regulation

• Operon: proG PubMed

• Expression browser: proG PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed