MrnC

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  • Description: RNase Mini-III

Gene name mrnC
Synonyms yazC
Essential no
Product RNase Mini-III
Function maturation of 23S rRNA
Gene expression levels in SubtiExpress: mrnC
Metabolic function and regulation of this protein in SubtiPathways:
mrnC
MW, pI 16 kDa, 9.153
Gene length, protein length 429 bp, 143 aa
Immediate neighbours cysS, yacO
Sequences Protein DNA DNA_with_flanks
Genetic context
YazC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MrnC expression.png




























Categories containing this gene/protein

Rnases, translation

This gene is a member of the following regulons

T-box

The gene

Basic information

  • Locus tag: BSU00950

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: RNase III family (but lacks the dsRNA-binding domain)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: RplC binding to the precursor 23S rRNA stimulates MrnC activity PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism: T-box, overlaps a transcription terminator upstream of cysE: transcription antitermination PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Ciaran Condon, IBPC, Paris, France Homepage

David Bechhofer, Mount Sinai School, New York, USA Homepage

Your additional remarks

References