GatC

• Description: production of glutamyl-tRNA(Gln)
  
  

Gene name	gatC
Synonyms	yerL, yedA
Essential	yes PubMed
Product	glutamyl-tRNA(Gln) amidotransferase (subunit C)
Function	translation
Gene expression levels in SubtiExpress: gatC
Interactions involving this protein in SubtInteract: GatC
Metabolic function and regulation of this protein in SubtiPathways: tRNA charging
MW, pI	10 kDa, 4.596
Gene length, protein length	288 bp, 96 aa
Immediate neighbours	opuE, gatA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

translation, essential genes, phosphoproteins

The gene

Basic information

• Locus tag: BSU06670

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate (according to Swiss-Prot)

• Protein family: gatC family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:
  • phosphorylated on Arg-3 PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • GatA-GatB-GatC
  • (GatA-GatB-GatC)-GltX-trnS-Gln (the "transamidosome") PubMed, see a model of the interaction PubMed

• Localization:

Database entries

• Structure: 2DF4 (GatA-GatB-GatC complex from Staphylococcus aureus) PubMed

• UniProt: O06492

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: gatC PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: