PssA

• Description: phosphatidylserine synthase
  
  

Gene name	pssA
Synonyms	pss
Essential	no
Product	phosphatidylserine synthase
Function	biosynthesis of phospholipids
Gene expression levels in SubtiExpress: pssA
Metabolic function and regulation of this protein in SubtiPathways: Lipid synthesis
MW, pI	19 kDa, 7.881
Gene length, protein length	531 bp, 177 aa
Immediate neighbours	ybfK, ybfM
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis of lipids, cell envelope stress proteins (controlled by SigM, V, W, X, Y), membrane proteins

This gene is a member of the following regulons

SigX regulon

The gene

Basic information

• Locus tag: BSU02270

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: CDP-diacylglycerol + L-serine = CMP + (3-sn-phosphatidyl)-L-serine (according to Swiss-Prot)

• Protein family: CDP-alcohol phosphatidyltransferase class-I family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane at the septum PubMed

Database entries

• Structure:

• UniProt: P39823

• KEGG entry: [3]

• E.C. number: 2.7.8.8

Expression and regulation

• Operon: pssA-ybfM-psd PubMed

• Expression browser: pssA PubMed

• Sigma factor: SigA PubMed, SigX PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

K Matsumoto
Phosphatidylserine synthase from bacteria.
Biochim Biophys Acta: 1997, 1348(1-2);214-27
[PubMed:9370336] [WorldCat.org] [DOI] (P p)