OpuCB

• Description: glycine betaine/carnitine/choline ABC transporter
  
  

Gene name	opuCB
Synonyms	yvbD
Essential	no
Product	glycine betaine/carnitine/choline ABC transporter
Function	compatible solute transport
Gene expression levels in SubtiExpress: opuCB
Interactions involving this protein in SubtInteract: OpuCB
Metabolic function and regulation of this protein in SubtiPathways: Stress
MW, pI	23 kDa, 9.705
Gene length, protein length	651 bp, 217 aa
Immediate neighbours	opuCC, opuCA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, coping with hyper-osmotic stress, membrane proteins

The gene

Basic information

• Locus tag: BSU33820

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: CysTW subfamily (according to Swiss-Prot)

• Paralogous protein(s): OpuBB

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: OpuCA-(OpuCB-OpuCD)-OpuCC PubMed

• Localization: cell membrane PubMed

Database entries

• Structure:

• UniProt: O34878

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: opuCA-opuCB-opuCC-opuCD PubMed

• Expression browser: opuCB PubMed

• Sigma factor:

• Regulation:
  • induced by salt stress PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Tamara Hoffmann, Erhard Bremer
Protection of Bacillus subtilis against cold stress via compatible-solute acquisition.
J Bacteriol: 2011, 193(7);1552-62
[PubMed:21296969] [WorldCat.org] [DOI] (I p)

R M Kappes, B Kempf, S Kneip, J Boch, J Gade, J Meier-Wagner, E Bremer
Two evolutionarily closely related ABC transporters mediate the uptake of choline for synthesis of the osmoprotectant glycine betaine in Bacillus subtilis.
Mol Microbiol: 1999, 32(1);203-16
[PubMed:10216873] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)

G Nau-Wagner, J Boch, Le Good JA, E Bremer
High-affinity transport of choline-O-sulfate and its use as a compatible solute in Bacillus subtilis.
Appl Environ Microbiol: 1999, 65(2);560-8
[PubMed:9925583] [WorldCat.org] [DOI] (P p)