OpcR

• Description: transcriptional repressor of the opuBA-opuBB-opuBC-opuBD and opuCA-opuCB-opuCC-opuCD operons
  
  

Gene name	opcR
Synonyms	yvbF
Essential	no
Product	choline-responsible transcription repressor
Function	regulation of choline uptake
Gene expression levels in SubtiExpress: opcR
MW, pI	21 kDa, 5.837
Gene length, protein length	555 bp, 185 aa
Immediate neighbours	opuCA, yvbG
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

miscellaneous metabolic pathways, transcription factors and their control, coping with hyper-osmotic stress

The gene

Basic information

• Locus tag: BSU33840

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • transcriptional repression of the opuBA-opuBB-opuBC-opuBD and opuCA-opuCB-opuCC-opuCD operons in the presence of choline PubMed
• Protein family:

• Paralogous protein(s): YvaV

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O34709

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: opcR PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Chun-Hao Lee, Tien-Yu Wu, Gwo-Chyuan Shaw
Involvement of OpcR, a GbsR-type transcriptional regulator, in negative regulation of two evolutionarily closely related choline uptake genes in Bacillus subtilis.
Microbiology (Reading): 2013, 159(Pt 10);2087-2096
[PubMed:23960087] [WorldCat.org] [DOI] (I p)