GalK

• Description: galactokinase
  
  

Gene name	galK
Synonyms	ipa-35d
Essential	no
Product	galactokinase
Function	galactose utilization
Gene expression levels in SubtiExpress: galK
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	43 kDa, 5.148
Gene length, protein length	1170 bp, 390 aa
Immediate neighbours	galT, gtaC
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of specific carbon sources

This gene is a member of the following regulons

CcpA regulon

The gene

Basic information

• Locus tag: BSU38200

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP + D-galactose = ADP + alpha-D-galactose 1-phosphate (according to Swiss-Prot)

• Protein family: GalK subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• Structure: 1PIE (from Lactococcus lactis, 43% identity, 60% similarity) PubMed

• UniProt: P39574

• KEGG entry: [3]

• E.C. number: 2.7.1.6

Expression and regulation

• Operon:
  • galK-galT PubMed
  • ywcC-gtaC-galK-galT PubMed

• Expression browser: galK PubMed

• Sigma factor:

• Regulation:
  • repressed by glucose (CcpA) PubMed

• Regulatory mechanism:
  • CcpA: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: