DppA

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  • Description: D-alanyl-aminopeptidase

Gene name dppA
Synonyms dciAA
Essential no
Product D-alanyl-aminopeptidase
Function degradation of cell wall peptides
Gene expression levels in SubtiExpress: dppA
Metabolic function and regulation of this protein in SubtiPathways:
Alternative nitrogen sources
MW, pI 30 kDa, 5.19
Gene length, protein length 822 bp, 274 aa
Immediate neighbours proG, dppB
Sequences Protein DNA Advanced_DNA
Genetic context
DppA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
DppA expression.png
























Categories containing this gene/protein

utilization of nitrogen sources other than amino acids, phosphoproteins

This gene is a member of the following regulons

CodY regulon

The gene

Basic information

  • Locus tag: BSU12920

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase M55 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylated on ser/ thr/ tyr PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed by glucose (2.9-fold) PubMed
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References