QoxB

• Description: cytochrome aa3 quinol oxidase (subunit I)
  
  

Gene name	qoxB
Synonyms	ipa-38d
Essential	no
Product	cytochrome aa3 quinol oxidase (subunit I)
Function	respiration
Gene expression levels in SubtiExpress: qoxB
MW, pI	73 kDa, 8.848
Gene length, protein length	1947 bp, 649 aa
Immediate neighbours	qoxC, qoxA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

respiration, membrane proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

• Locus tag: BSU38160

Phenotypes of a mutant

• inactivation of qoxB restores beta-lactam resistance in a sigM mutant PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Additional information

• A mutation was found in this gene after evolution under relexed selection for sporulation PubMed

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Ubiquinol-8 + O₂ = Ubiquinone-8 + H₂O (according to Swiss-Prot)

• Protein family: heme-copper respiratory oxidase family (according to Swiss-Prot)

• Paralogous protein(s): CtaD

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane PubMed

Database entries

• Structure:

• UniProt: P34956

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: qoxA-qoxB-qoxC-qoxD PubMed

• Expression browser: qoxB PubMed

• Sigma factor:

• Regulation:
  • RelA dependent downregulation (Class I) during stringent response PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed