KtrB

• Description: high affinity potassium transporter KtrA-KtrB, integral membrane subunit
  
  

Gene name	ktrB
Synonyms	yubG
Essential	no
Product	high affinity potassium transporter KtrA-KtrB, integral membrane subunit (proton symport)
Function	potassium uptake
Gene expression levels in SubtiExpress: ktrB
Interactions involving this protein in SubtInteract: KtrB
Metabolic function and regulation of this protein in SubtiPathways: Metal ion homeostasis, Stress
MW, pI	48 kDa, 10.116
Gene length, protein length	1335 bp, 445 aa
Immediate neighbours	ktrA, yubF
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), coping with hyper-osmotic stress, membrane proteins

This gene is a member of the following regulons

YdaO riboswitch

The gene

Basic information

• Locus tag: BSU31100

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): KtrD

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • KtrB forms dimers PubMed
  • KtrA-KtrB PubMed, composed of an octameric KtrA ring and two KtrB dimers PubMed

• Localization: integral membrane protein PubMed

Database entries

• Structure:
  • 4J7C (the KtrA-KtrB complex) PubMed

• UniProt: O32081

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: ktrA-ktrB PubMed

• Expression browser: ktrB PubMed

• Sigma factor:

• Regulation:
  • induced if the energy charge is low (ydaO riboswitch) PubMed

• Regulatory mechanism:
  • expression is controlled via termination antitermination by the ydaO riboswitch PubMed

• Additional information:

Biological materials

• Mutant:
  • 1A954 ( ktrB::kan), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Erhard Bremer, University of Marburg, Germany homepage