YtbE

• Description: putative aldo/keto reductase, may be involved in detoxification
  
  

Gene name	ytbE
Synonyms
Essential	yes PubMed
Product	putative aldo/keto reductase
Function	unknown
Gene expression levels in SubtiExpress: ytbE
MW, pI	31 kDa, 4.786
Gene length, protein length	840 bp, 280 aa
Immediate neighbours	ytbD, ytaG
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

poorly characterized/ putative enzymes, membrane proteins, essential genes

The gene

Basic information

• Locus tag: BSU29050

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: Nudix hydrolase, aldo/keto reductase family (according to Swiss-Prot)

• Paralogous protein(s): YvgN

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure: 3A3D

• UniProt: O34678

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: ytbE PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Jian Lei, Yan-Feng Zhou, Lan-Fen Li, Xiao-Dong Su
Structural and biochemical analyses of YvgN and YtbE from Bacillus subtilis.
Protein Sci: 2009, 18(8);1792-800
[PubMed:19585557] [WorldCat.org] [DOI] (I p)

Helena B Thomaides, Ella J Davison, Lisa Burston, Hazel Johnson, David R Brown, Alison C Hunt, Jeffery Errington, Lloyd Czaplewski
Essential bacterial functions encoded by gene pairs.
J Bacteriol: 2007, 189(2);591-602
[PubMed:17114254] [WorldCat.org] [DOI] (P p)