RodZ

• Description: required for cell shape determination
  
  

Gene name	rodZ
Synonyms	ymfM
Essential	no
Product	morphogenic protein
Function	required for cell shape determination
Gene expression levels in SubtiExpress: rodZ
MW, pI	23 kDa, 4.679
Gene length, protein length	639 bp, 213 aa
Immediate neighbours	ymfK/2, pgsA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell shape, membrane proteins

The gene

Basic information

• Locus tag: BSU16910

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • part of the cell wall biosynthetic complex PubMed

• Localization: membrane protein (according to Swiss Prot)

Database entries

• Structure:

• UniProt: O31771

• KEGG entry: [2]

• E.C. number:

Additional information

overexpression results in growth inhibition in minimal medium (in the absence of Mg2+ ) PubMed

Expression and regulation

• Operon:

• Expression browser: rodZ PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Adriano Henriques, Lisbon, Portugal homepage

References

Ethan C Garner, Remi Bernard, Wenqin Wang, Xiaowei Zhuang, David Z Rudner, Tim Mitchison
Coupled, circumferential motions of the cell wall synthesis machinery and MreB filaments in B. subtilis.
Science: 2011, 333(6039);222-5
[PubMed:21636745] [WorldCat.org] [DOI] (I p)

Julia Domínguez-Escobar, Arnaud Chastanet, Alvaro H Crevenna, Vincent Fromion, Roland Wedlich-Söldner, Rut Carballido-López
Processive movement of MreB-associated cell wall biosynthetic complexes in bacteria.
Science: 2011, 333(6039);225-8
[PubMed:21636744] [WorldCat.org] [DOI] (I p)

S Anisah Alyahya, Roger Alexander, Teresa Costa, Adriano O Henriques, Thierry Emonet, Christine Jacobs-Wagner
RodZ, a component of the bacterial core morphogenic apparatus.
Proc Natl Acad Sci U S A: 2009, 106(4);1239-44
[PubMed:19164570] [WorldCat.org] [DOI] (I p)