CitH

• Description: sporulation-specific secondary transporter of divalent metal ions/citrate complexes
  
  

Gene name	citH
Synonyms	yxiQ
Essential	no
Product	secondary transporter of divalent metal ions/citrate complexes
Function	citrate uptake
Gene expression levels in SubtiExpress: citH
Metabolic function and regulation of this protein in SubtiPathways: metal ion homeostasis
MW, pI	45 kDa, 9.278
Gene length, protein length	1278 bp, 426 aa
Immediate neighbours	katE, bglS
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, utilization of specific carbon sources, sporulation proteins, membrane proteins

The gene

Basic information

• Locus tag: BSU39060

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): CitM

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P42308

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: citH PubMed

• Expression browser: citH PubMed

• Sigma factor: SigE and/ or SigF PubMed

• Regulation:
  • expressed during sporulation PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

B P Krom, J B Warner, W N Konings, J S Lolkema
Complementary metal ion specificity of the metal-citrate transporters CitM and CitH of Bacillus subtilis.
J Bacteriol: 2000, 182(22);6374-81
[PubMed:11053381] [WorldCat.org] [DOI] (P p)

A Boorsma, M E van der Rest, J S Lolkema, W N Konings
Secondary transporters for citrate and the Mg(2+)-citrate complex in Bacillus subtilis are homologous proteins.
J Bacteriol: 1996, 178(21);6216-22
[PubMed:8892821] [WorldCat.org] [DOI] (P p)