RpsD

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Gene name rpsD
Synonyms
Essential yes PubMed
Product ribosomal protein S4 (BS4)
Function translation
Gene expression levels in SubtiExpress: rpsD
Interactions involving this protein in SubtInteract: RpsD
MW, pI 22 kDa, 10.243
Gene length, protein length 600 bp, 200 aa
Immediate neighbours ytrP, tyrS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RpsD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RpsD expression.png















Categories containing this gene/protein

translation, essential genes, universally conserved proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU29660

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1C06 (Geobacillus stearothermophilus)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Matthew A Lauber, William E Running, James P Reilly
B. subtilis ribosomal proteins: structural homology and post-translational modifications.
J Proteome Res: 2009, 8(9);4193-206
[PubMed:19653700] [WorldCat.org] [DOI] (P p)

T Inaoka, K Kasai, K Ochi
Construction of an in vivo nonsense readthrough assay system and functional analysis of ribosomal proteins S12, S4, and S5 in Bacillus subtilis.
J Bacteriol: 2001, 183(17);4958-63
[PubMed:11489846] [WorldCat.org] [DOI] (P p)

F J Grundy, T M Henkin
Characterization of the Bacillus subtilis rpsD regulatory target site.
J Bacteriol: 1992, 174(21);6763-70
[PubMed:1400226] [WorldCat.org] [DOI] (P p)

F J Grundy, T M Henkin
The rpsD gene, encoding ribosomal protein S4, is autogenously regulated in Bacillus subtilis.
J Bacteriol: 1991, 173(15);4595-602
[PubMed:1906866] [WorldCat.org] [DOI] (P p)

T M Henkin, G H Chambliss, F J Grundy
Bacillus subtilis mutants with alterations in ribosomal protein S4.
J Bacteriol: 1990, 172(11);6380-5
[PubMed:2121712] [WorldCat.org] [DOI] (P p)

F J Grundy, T M Henkin
Cloning and analysis of the Bacillus subtilis rpsD gene, encoding ribosomal protein S4.
J Bacteriol: 1990, 172(11);6372-9
[PubMed:1699930] [WorldCat.org] [DOI] (P p)

T M Henkin, G H Chambliss
Genetic mapping of a mutation causing an alteration in Bacillus subtilis ribosomal protein S4.
Mol Gen Genet: 1984, 193(2);364-9
[PubMed:6420647] [WorldCat.org] [DOI] (P p)