GlnT

Gene name	glnT
Synonyms	ybgH
Essential	no
Product	glutamine transporter (proton symport)
Function	glutamine uptake
Gene expression levels in SubtiExpress: glnT
Metabolic function and regulation of this protein in SubtiPathways: Ammonium/ glutamate, Ala, Gly, Ser
MW, pI	49 kDa, 10.132
Gene length, protein length	1389 bp, 463 aa
Immediate neighbours	ybgG, glsA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, biosynthesis/ acquisition of amino acids, glutamate metabolism, utilization of amino acids, membrane proteins

This gene is a member of the following regulons

GlnL regulon

The gene

Basic information

• Locus tag: BSU02420

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: sodium:alanine (SAF) symporter family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O31464

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: glsA-glnT PubMed

• Expression browser: glnT PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced in the presence of glutamine (GlnL) PubMed

• Regulatory mechanism:
  • GlnL: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Takenori Satomura, Daisuke Shimura, Kei Asai, Yoshito Sadaie, Kazutake Hirooka, Yasutaro Fujita
Enhancement of glutamine utilization in Bacillus subtilis through the GlnK-GlnL two-component regulatory system.
J Bacteriol: 2005, 187(14);4813-21
[PubMed:15995196] [WorldCat.org] [DOI] (P p)