DppA

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  • Description: D-alanyl-aminopeptidase

Gene name dppA
Synonyms dciAA
Essential no
Product D-alanyl-aminopeptidase
Function degradation of cell wall peptides
Metabolic function and regulation of this protein in SubtiPathways:
Alternative nitrogen sources
MW, pI 30 kDa, 5.19
Gene length, protein length 822 bp, 274 aa
Immediate neighbours proG, dppB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
DppA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
DppA expression.png
























Categories containing this gene/protein

utilization of nitrogen sources other than amino acids, phosphoproteins

This gene is a member of the following regulons

CodY regulon

The gene

Basic information

  • Locus tag: BSU12920

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase M55 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylated on ser/ thr/ tyr PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed by glucose (2.9-fold) PubMed
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References