YydA

• Description: similar to pseudouridine methyltransferase
  
  

Gene name	yydA
Synonyms
Essential	no
Product	similar to pseudouridine methyltransferase
Function	may be involved in maturation of 23S rRNA
MW, pI	17 kDa, 9.314
Gene length, protein length	477 bp, 159 aa
Immediate neighbours	yydB, yycS
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

translation

This gene is a member of the following regulons

DnaA regulon

The gene

Basic information

• Locus tag: BSU40230

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine (according to Swiss-Prot)

• Protein family: RNA methyltransferase rlmH family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure: 1TO0

• UniProt: Q45601

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • DnaA: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Rya Ero, Lauri Peil, Aivar Liiv, Jaanus Remme
Identification of pseudouridine methyltransferase in Escherichia coli.
RNA: 2008, 14(10);2223-33
[PubMed:18755836] [WorldCat.org] [DOI] (I p)

Elzbieta Purta, Katarzyna H Kaminska, Joanna M Kasprzak, Janusz M Bujnicki, Stephen Douthwaite
YbeA is the m3Psi methyltransferase RlmH that targets nucleotide 1915 in 23S rRNA.
RNA: 2008, 14(10);2234-44
[PubMed:18755835] [WorldCat.org] [DOI] (I p)

Shu Ishikawa, Yoshitoshi Ogura, Mika Yoshimura, Hajime Okumura, Eunha Cho, Yoshikazu Kawai, Ken Kurokawa, Taku Oshima, Naotake Ogasawara
Distribution of stable DnaA-binding sites on the Bacillus subtilis genome detected using a modified ChIP-chip method.
DNA Res: 2007, 14(4);155-68
[PubMed:17932079] [WorldCat.org] [DOI] (P p)