HemX

• Description: negative effector of the concentration of HemA
  
  

Gene name	hemX
Synonyms
Essential	no
Product	regulatory protein, protease?
Function	heme biosynthesis
MW, pI	31 kDa, 9.28
Gene length, protein length	828 bp, 276 aa
Immediate neighbours	hemC, hemA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

PerR regulon

The gene

Basic information

• Locus tag: BSU28160

Expression

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P16645

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: hemA-hemX-hemC-hemD-hemB-hemL PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by hydrogen peroxide (PerR) PubMed

• Regulatory mechanism:
  • PerR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: