SigM regulon

Regulator	SigM
Overview on the regulons (wiki page) Overview on the regulons (Excel file)

• The SigM regulon is induced by cell wall-active antibiotics like vancomycin and bacitracin, as well as a variety of other stresses

Genes in this regulon

• abh
• bcrC
• coaX
• ddl
• disA
• divIB
• divIC
• dltA
• dltB
• dltC
• dltD
• dltE
• fatR
• ftsH
• hprT
• ispD
• metA
• minC
• minD
• mreB
• mreC
• mreD
• murB
• murF
• ponA
• pbpX
• radC
• rapD
• recU
• rodA
• sbp
• secDF
• sigM
• spx
• tagT
• tilS
• ugtP
• yacC
• yacL
• yceC
• yceD
• yceE
• yceF
• yceG
• yceH
• ycgQ
• ycgR
• ydaH
• yebC
• yfnI
• yhdK
• yhdL
• yjbC
• ylxW
• ylxX
• yngC
• ypbG
• ypuA
• ypuD
• yqjL
• yrhH
• yrhJ
• ytpA
• ytpB
• ywaC
• ywbN
• ywbO
• ywnJ

Important publications on the SigM regulon

Warawan Eiamphungporn, John D Helmann
The Bacillus subtilis sigma(M) regulon and its contribution to cell envelope stress responses.
Mol Microbiol: 2008, 67(4);830-48
[PubMed:18179421] [WorldCat.org] [DOI] (P p)

Thorsten Mascher, Anna-Barbara Hachmann, John D Helmann
Regulatory overlap and functional redundancy among Bacillus subtilis extracytoplasmic function sigma factors.
J Bacteriol: 2007, 189(19);6919-27
[PubMed:17675383] [WorldCat.org] [DOI] (P p)

Adrian J Jervis, Penny D Thackray, Chris W Houston, Malcolm J Horsburgh, Anne Moir
SigM-responsive genes of Bacillus subtilis and their promoters.
J Bacteriol: 2007, 189(12);4534-8
[PubMed:17434969] [WorldCat.org] [DOI] (P p)