SpoIVA

• Description: required for proper spore cortex formation and coat assembly
  
  

Gene name	spoIVA
Synonyms	spoVP
Essential	no
Product	basement layer protein for spore coat assembly
Function	spore cortex formation and coat assembly
MW, pI	55 kDa, 4.546
Gene length, protein length	1476 bp, 492 aa
Immediate neighbours	hbs, yphF
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU22800

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

sporulation proteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: SpoIVA-SpoVID PubMed, SpoIVA-SafA PubMed, SpoIVA-SpoVM-SpoVID PubMed

• Localization:

Database entries

• Structure:

• UniProt: P35149

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: spoIVA PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed early during sporulation in the mother cell (SigE, SpoIIID) PubMed

• Regulatory mechanism:
  • SpoIIID: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: