BmrC

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  • Description: multidrug ABC transporter (ATP-binding protein), also involved in the signalling pathway to activate KinA at the onset of sporulation

Gene name yheI
Synonyms
Essential no
Product multidrug ABC transporter (ATP-binding protein)
Function multiple antibiotic resistance
MW, pI 64 kDa, 6.252
Gene length, protein length 1755 bp, 585 aa
Immediate neighbours yheJ, yheH
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YheI context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU09710

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: has both a membrane-spanning and an ATP-binding domain PubMed
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Cristina Torres, Carmen Galián, Christoph Freiberg, Jean-Raphaël Fantino, Jean-Michel Jault
The YheI/YheH heterodimer from Bacillus subtilis is a multidrug ABC transporter.
Biochim Biophys Acta: 2009, 1788(3);615-22
[PubMed:19167342] [WorldCat.org] [DOI] (P p)

Sanae Fukushima, Mika Yoshimura, Taku Chibazakura, Tsutomu Sato, Hirofumi Yoshikawa
The putative ABC transporter YheH/YheI is involved in the signalling pathway that activates KinA during sporulation initiation.
FEMS Microbiol Lett: 2006, 256(1);90-7
[PubMed:16487324] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)