RapD

• Description: response regulator aspartate phosphatase, controls ComA activity
  
  

Gene name	rapD
Synonyms	ywpA
Essential	no
Product	response regulator aspartate phosphatase
Function	control of ComA-dependent gene expression
MW, pI	41 kDa, 7.691
Gene length, protein length	1062 bp, 354 aa
Immediate neighbours	ywpB, flhP
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU36380

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: control of ComA-dependent gene expression PubMed

• Protein family: RAP family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P94583

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: rapD PubMed

• Sigma factor: SigA PubMed, SigX PubMed

• Regulation:
  • repressed by RghR PubMed

• Regulatory mechanism:
  • RghR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Mitsuo Ogura, Yasutaro Fujita
Bacillus subtilis rapD, a direct target of transcription repression by RghR, negatively regulates srfA expression.
FEMS Microbiol Lett: 2007, 268(1);73-80
[PubMed:17227471] [WorldCat.org] [DOI] (P p)

X Huang, J D Helmann
Identification of target promoters for the Bacillus subtilis sigma X factor using a consensus-directed search.
J Mol Biol: 1998, 279(1);165-73
[PubMed:9636707] [WorldCat.org] [DOI] (P p)