AlsR

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• Description: transcriptional activator of the alsS-alsD operon<br/><br/>

Gene name	alsR
Synonyms
Essential	no
Product	transcriptional activator(LysR family)
Function	regulation of acetoin synthesis (alsS-alsD)
Metabolic function and regulation of this protein in SubtiPathways: <br/>Central C-metabolism
MW, pI	34 kDa, 7.288
Gene length, protein length	906 bp, 302 aa
Immediate neighbours	alsS, ywrK
Get the DNA and protein sequences <br/> (Barbe et al., 2009)
Genetic context <br/> <div align="right"> <small>This image was kindly provided by SubtiList</small></div>

<br/><br/><br/><br/><br/><br/>

The gene

Basic information

• Locus tag: BSU36020

Phenotypes of a mutant

no acetoin production

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: binds the promoter region of the alsS-alsD operon in the presence of acetate, activates transcription

• Protein family: LysR family of transcription factors

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: Q04778

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant: AMBs3 (spc), available in the Stülke lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Elisabeth Härtig, Braunschweig, Germany Homepage

References

<pubmed>7685336, </pubmed>