NucA

• Description: membrane-associated nuclease, catalyzes DNA cleavage during transformation
  
  

Gene name	nucA
Synonyms	comI
Essential	no
Product	membrane-associated nuclease
Function	genetic transformation, DNA uptake
MW, pI	16 kDa, 4.677
Gene length, protein length	441 bp, 147 aa
Immediate neighbours	nin, tlpC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU03430

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot), integral membrane protein PubMed

Database entries

• Structure:

• Swiss prot entry: P12667

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: nucA-nin PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: