SsuD

• Description: aliphatic sulfonate monooxygenase
  
  

Gene name	ssuD
Synonyms	ygcA, yzeC
Essential	no
Product	aliphatic sulfonate monooxygenase
Function	sulfonate reduction
MW, pI	41 kDa, 5.369
Gene length, protein length	1128 bp, 376 aa
Immediate neighbours	ssuC, ygaN
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU08860

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: An alkanesufonate (R-CH(2)-SO₃H) + FMNH₂ + O₂ = an aldehyde (R-CHO) + FMN + sulfite + H₂O (according to Swiss-Prot)

• Protein family: ssuD family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• Swiss prot entry: P40402

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ssuB-ssuA-ssuC-ssuD-ygaN

• Sigma factor: SigA

• Regulation: repressed in the presence of cysteine (CymR) PubMed
  • repressed in the presence of cysteine (CymR) PubMed

• Regulatory mechanism: CymR: transcription repression PubMed
  • CymR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Sergine Even, Pierre Burguière, Sandrine Auger, Olga Soutourina, Antoine Danchin, Isabelle Martin-Verstraete
Global control of cysteine metabolism by CymR in Bacillus subtilis.
J Bacteriol: 2006, 188(6);2184-97
[PubMed:16513748] [WorldCat.org] [DOI] (P p)

Jan R van der Ploeg, Nicola J Cummings, Thomas Leisinger, Ian F Connerton
Bacillus subtilis genes for the utilization of sulfur from aliphatic sulfonates.
Microbiology (Reading): 1998, 144 ( Pt 9);2555-2561
[PubMed:9782504] [WorldCat.org] [DOI] (P p)

1. van der Ploeg JR, Cummings NJ, Leisinger T, Connerton IF. (1998) Bacillus subtilis genes for the utilization of sulfur from aliphatic sulfonates. Microbiology Sep;144(Pt9): 2555-61. PubMed
2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed