T-box

From SubtiWiki
Revision as of 19:47, 27 May 2009 by Jstuelk (talk | contribs) (Genes controled by T-box element)
Jump to: navigation, search

The T-box element is a RNA switch that controls genes involved in amino acid metabolism.

In the absence of an amino acid, the uncharged tRNA binds the T-box region in the leader region of the mRNA of the controlled gene/ operon and thereby prevents the formation of a transcription terminator. The result is gene expression of the target gene in the absence of the specific amino acid.

Genes controlled by T-box elements

  • Induction by cysteine limitation
  • Induction by tryptophan limitation