SodA

• Description: superoxide dismutase, general stress protein
  
  

Gene name	sodA
Synonyms	yqgD
Essential	no
Product	superoxide dismutase
Function	detoxification of oxygen radicals
MW, pI	22 kDa, 5.203
Gene length, protein length	606 bp, 202 aa
Immediate neighbours	yqgE, yqgC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag:

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: 2 superoxide + 2 H⁺ = O₂ + H₂O₂ (according to Swiss-Prot)

• Protein family: iron/manganese superoxide dismutase family (according to Swiss-Prot)

• Paralogous protein(s): SodF

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylation on Thr-34 AND Thr-70 PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure: 2RCV

• Swiss prot entry: P54375

• KEGG entry: BSU25020

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor: SigB PubMed

• Regulation: induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Höper et al. (2005) Comprehensive Characterization of the Contribution of Individual SigB-Dependent General Stress Genes to Stress Resistance of Bacillus subtilis. J. Bact. 187: 2810-2826 PubMed
2. Macek et al. (2007) The serine/ threonine/ tyrosine phosphoproteome of the model bacterium Bacillus subtilis. Mol. Cell. Proteomics 6: 697-707 PubMed
3. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed