PtsH

• Description: General (non sugar-specific) component of the sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.
  
  

Gene name	ptsH
Synonyms
Essential	write here
Product	histidine-containing phosphocarrier protein of the PTS
Function	mediates carbon catabolite repression (CCR)
MW, pI	9,1 kDa, 4.58
Gene length, protein length	264 bp, 88 amino acids
Immediate neighbours	ptsG, ptsI
Gene sequence (+200bp)	Protein sequence
Genetic context File:GenE context.gif

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry:[2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Protein HPr N(pi)-phospho-L-histidine + protein EIIA = protein HPr + protein EIIA N(tau)-phospho-L-histidine

• Protein family: HPr family

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: HPr Domain (2–88)

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: GapA-PtsH, PtsH-MtlR, PtsH-LicR, PtsH-LevR, PtsH-ManR, YesS-PtsH (HPr-His-P), PtsH-CcpA, PtsH-RbsR, HprK-PtsH

• Localization: Cytoplasm

Database entries

• Structure:

• Swiss prot entry: [3]

• KEGG entry:

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

References

1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed