SmiA

• Description: adaptor protein for LonA-mediated degradation of SwrA,inhibitor of swarming motility
  
  

Gene name	smiA
Synonyms	yvzG
Essential	no
Product	adaptor protein for LonA-mediated degradation of SwrA
Function	control of swarming motility
Gene expression levels in SubtiExpress: smiA
MW, pI	15 kDa, 4.673
Gene length, protein length	375 bp, 125 aa
Immediate neighbours	yvyD, fliT
Gene sequence (+200bp)	Protein sequence
Genetic context File:YvzG context.gif
Expression at a glance   PubMed

Categories containing this gene/protein

motility and chemotaxis

The gene

Basic information

• Locus tag: BSU35319

Phenotypes of a mutant

A mutation in smiA suppresses the motility defect of a lytC mutant PubMed

Database entries

• BsubCyc: BSU35319

• DBTBS entry: no entry

• SubtiList entry: no entry

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • LonA-SmiA PubMed
  • SmiA-SwrA (degradation) PubMed

• Localization:

Database entries

• BsubCyc: BSU35319

• Structure:

• UniProt: C0H3R9

• KEGG entry:

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: smiA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant: available in the Daniel Kearns lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Daniel Kearns, Indiana University, Bloomington, USA, homepage

References

Sampriti Mukherjee, Anna C Bree, Jing Liu, Joyce E Patrick, Peter Chien, Daniel B Kearns
Adaptor-mediated Lon proteolysis restricts Bacillus subtilis hyperflagellation.
Proc Natl Acad Sci U S A: 2015, 112(1);250-5
[PubMed:25538299] [WorldCat.org] [DOI] (I p)

Rui Chen, Sarah B Guttenplan, Kris M Blair, Daniel B Kearns
Role of the sigmaD-dependent autolysins in Bacillus subtilis population heterogeneity.
J Bacteriol: 2009, 191(18);5775-84
[PubMed:19542270] [WorldCat.org] [DOI] (I p)