BceS

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  • Description: two-component sensor kinase, regulation of bceA-bceB in response to bacitracin, plectasin, mersacidin and actagardine

Gene name bceS
Synonyms ytsB
Essential no
Product two-component sensor kinase (OmpR family)
Function resistance against toxic peptides
Gene expression levels in SubtiExpress: bceS
Interactions involving this protein in SubtInteract: BceS
MW, pI 38 kDa, 5.939
Gene length, protein length 1002 bp, 334 aa
Immediate neighbours bceA, bceR
Sequences Protein DNA DNA_with_flanks
Genetic context
YtsB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
BceS expression.png















Categories containing this gene/protein

protein modification, transcription factors and their control, resistance against toxins/ antibiotics, membrane proteins, phosphoproteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU30390

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of BceR
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain
  • Modification: autophosphorylation on a His residue
  • Cofactor(s):
  • Effectors of protein activity:
    • binding of BceB in the absence of bacitracin inhibits BceS autophosphorylation PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References