YaaA

• Description: ribosome assembly factor, participates in the assembly of the 50S subunit of the ribosome
  
  

Gene name	yaaA
Synonyms
Essential
Product	ribosome assembly factor
Function	assembly of the 50S subunit of the ribosome
Gene expression levels in SubtiExpress: YaaA
MW, pI	7 kDa, 4.332
Gene length, protein length	213 bp, 71 aa
Immediate neighbours	dnaN, recF
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

translation

The gene

Basic information

• Locus tag: BSU00030

Phenotypes of a mutant

• enhanced expression suppresses the defects of a temperature-sensitive rplB mutant PubMed

Database entries

• BsubCyc: BSU00030

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU00030

• Structure:

• UniProt: P05650

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yaaA-recF-yaaB-gyrB PubMed

• Expression browser: yaaA PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Shota Suzuki, Osamu Tanigawa, Genki Akanuma, Hideaki Nanamiya, Fujio Kawamura, Kazumi Tagami, Naofumi Nomura, Teppei Kawabata, Yasuhiko Sekine
Enhanced expression of Bacillus subtilis yaaA can restore both the growth and the sporulation defects caused by mutation of rplB, encoding ribosomal protein L2.
Microbiology (Reading): 2014, 160(Pt 6);1040-1053
[PubMed:24637032] [WorldCat.org] [DOI] (I p)

N Ogasawara, S Moriya, H Yoshikawa
Structure and function of the region of the replication origin of the Bacillus subtilis chromosome. IV. Transcription of the oriC region and expression of DNA gyrase genes and other open reading frames.
Nucleic Acids Res: 1985, 13(7);2267-79
[PubMed:2987848] [WorldCat.org] [DOI] (P p)