HutU
Revision as of 15:12, 2 April 2014 by 134.76.38.147 (talk)
- Description: urocanase
Gene name | hutU |
Synonyms | |
Essential | no |
Product | urocanase |
Function | histidine utilization |
Gene expression levels in SubtiExpress: hutU | |
Metabolic function and regulation of this protein in SubtiPathways: hutU | |
MW, pI | 60 kDa, 5.664 |
Gene length, protein length | 1656 bp, 552 aa |
Immediate neighbours | hutH, hutI |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
CcpA regulon, CodY regulon, HutP regulon
The gene
Basic information
- Locus tag: BSU39360
Phenotypes of a mutant
Database entries
- BsubCyc: BSU39360
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
- A mutation was found in this gene after evolution under relaxed selection for sporulation PubMed
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate = urocanate + H2O (according to Swiss-Prot)
- Protein family: urocanase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- BsubCyc: BSU39360
- Structure: 2FKN
- UniProt: P25503
- KEGG entry: [3]
- E.C. number: 4.2.1.49
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Robert A Bender
Regulation of the histidine utilization (hut) system in bacteria.
Microbiol Mol Biol Rev: 2012, 76(3);565-84
[PubMed:22933560]
[WorldCat.org]
[DOI]
(I p)
Original publications